About Us
This website is an independent resource created to share updates related to the ISEV Blood Task Force and Blood EVs. It is not affiliated with or endorsed by the International Society for Extracellular Vesicles (ISEV). Content is provided for informational purposes and reflects ongoing Task Force activities and materials as they evolve.
Working Groups
3
4
5
Collection, Handling, and Storage of Blood EV Samples
1
Focus: Pre-analytical best practices that protect EV integrity and improve reproducibility.
What we do: Benchmark key variables (e.g., tubes/anticoagulants, centrifugation, storage conditions) and publish clear SOPs, flowcharts, and training resources.
Quality Controls of Plasma and Serum
2
Quality Control of EV Preparations
Focus: Quality checks before EV isolation to ensure clean, comparable starting material.
What we do: Define indicators like hemolysis, lipemia, and contamination; validate reporting/QC frameworks; and run inter-lab studies plus dissemination workshops.
Focus: Minimal standards for evaluating EV prep quality, purity, and repeatability.
What we do: Build QC checklists and reporting guidelines; standardize characterization approaches (e.g., particle/protein measures, contaminants, key analytical methods); and validate standards through international comparisons.
Clinical and Translational Applications
Focus: Making blood EV research clinically useful and methodologically consistent.
What we do: Develop position papers and minimal criteria for biomarker discovery/validation and clinical-grade assays/therapies, while strengthening translational collaborations and clinical study pathways.
Focus: Making blood EV research clinically useful and methodologically consistent.
What we do: Develop position papers and minimal criteria for biomarker discovery/validation and clinical-grade assays/therapies, while strengthening translational collaborations and clinical study pathways.